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PostPosted: Mon Jun 23, 2008 4:43 pm 
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Joined: Thu Dec 20, 2007 7:23 pm
Posts: 1021
Location: Kingston
Food-Allergic Children With Asthma May Require Extra Emergency Medication

Quote:
New research findings suggest that some food-allergic children may not be equipped with enough potentially life-saving medication to reverse a severe allergic reaction.

According to research to be published in an upcoming issue of the Journal of Allergy and Clinical Immunology, a second dose of epinephrine - the drug of choice for treating severe allergic reactions - was needed in nearly 1-of-5 cases of food-induced anaphylaxis in children.

Nearly all patients who required multiple doses of epinephrine also suffered from asthma.

Though further studies are needed, these findings point to asthma as a risk factor for severe anaphylaxis and could influence how epinephrine is prescribed to children.

Many children and adults at risk of severe allergic reactions are currently advised to carry only a single epinephrine auto-injector, which is administered when a severe reaction occurs.

In her study article, lead author Kirsi M. Järvinen, MD, PhD, writes that "the recommendation to carry two doses of epinephrine should as minimum be extended to individuals with asthma and significant food allergies."


http://www.medicalnewstoday.com/articles/112377.php

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PostPosted: Tue Jun 24, 2008 6:40 am 
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Joined: Tue Mar 22, 2005 11:17 pm
Posts: 6615
Location: Ottawa
Wow, I didn't know there were statistics on that.

Thanks for the information- I have always carried at least two doses but I thought it was in case one auto-injector malfunctioned. The possibility of a second dose being required was always there but played down as not so likely.

My understanding, and I may be wrong, but the epinephrine halts the reaction and starts to reverse it. So...if it is given at the beginning of a reaction (when symptoms start but before major swelling etc has occurred) less medication should be required (less likely to need a second dose).

Any time that dd experiences allergic reactions involving two systems, after eating a food, I am giving the Epi-Pen regardless of how severe the symptoms are. Because she is at risk is enough reason for me.

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Daughter: asthma, allergies to egg, milk, peanuts, tree nuts, most legumes (not soy and green beans) & penicillin. Developing hayfever type allergies.
Husband: no allergies
Me: Oral Allergy Syndrome, Allergic to Birch trees


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PostPosted: Thu Jun 26, 2008 11:18 pm 
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Joined: Tue Nov 29, 2005 4:04 pm
Posts: 2044
Location: Gatineau, Quebec
Quote:
My understanding, and I may be wrong, but the epinephrine halts the reaction and starts to reverse it. So...if it is given at the beginning of a reaction (when symptoms start but before major swelling etc has occurred) less medication should be required (less likely to need a second dose).


This would be another good "ask the allergist" question, I think, because I'm not sure if that is true or not, Susan. Do you want to submit it? If not, I will!

It is very good to hear about this, even though it is a bit scary... My youngest son used to carry 2 EpiPens at all times, and then I decided to relax a bit - although at school he actually has 3 extras (classroom, daycare, and teacher's lounge) and I always carry a Twinject. But perhaps his next EBelt will be a double one... or I will dig out the very old one (hand-me-down) that he used to wear.

K.

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Karen, proud Mom of
- DS1 (12 yrs): allergic to cashews, pistachios, Brazil nuts, potatoes, some legumes, some fish, pumpkin seeds; OAS
- DS2 (1o yrs): ana. to dairy, eggs, peanuts; asthma


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